Introduction & Scale-Up of Postpartum Hemorrhage Products
The Postpartum Hemorrhage Product Catalytic Opportunity Fund (PPH COF) is a flexible pool of funds to support government-led, catalytic activities to introduce and scale-up priority and evidence-based, lifesaving medicines and medical devices that prevent, detect, and treat PPH, a leading cause of maternal mortality, in low and lower-middle-income countries.
Catalytic opportunities eligible for funding are broadly defined as activities that address key targeted barriers or unlock critical enablers to accelerate and sustain access to priority PPH products.
Opportunities should demonstrate how they will lead to tangible, time-bound results for introduction and scale up. PPH COF proposals must be government-endorsed to advance national priorities, clearly connecting to the country's broader, comprehensive approach for PPH management, and should leverage and build sustainable processes, systems, and resources for introduction and scale-up.
Announcements & Submission Deadlines
We’re excited to announce the reopening of the COF’s small-grants mechanism for PPH products. We are now accepting new applications.
Join our upcoming webinar on August 13 at 9:00 AM EST for an informational session reviewing the PPH COF scope, changes, and application process. We welcome your participation, and you can Register Here.
Ready to Apply? We strongly encourage all prospective applicants to review the PPH COF Readiness Tool Checklist to assess alignment with the updated criteria. Please refer to the COF Overview as a key resource when developing your proposal. It provides essential context on the challenges of PPH, outlines the principles and vision of the COF, and details the activities that fall within scope. This background will help ensure your proposal aligns with COF’s priorities and goals.
The upcoming submission deadline is Thursday, September 25 by 5:00 PM WAT.
All applicants must submit a short Expression of Interest (EOI) before applying, which can be found here. The upcoming EOI deadline is Monday, September 1 at 5:00 PM WAT.
Eligibility and Requirements
Interventions must meet the definition of “catalytic:” one-time investments that address key targeted barriers or unlock critical enablers to accelerate and sustain access to priority PPH products.
Be implemented in an eligible country: Benin, the Democratic Republic of the Congo, Ethiopia, Ghana, Guinea, Kenya, Lesotho, Liberia, Madagascar, Malawi, Nigeria, Rwanda, Senegal, the United Republic of Tanzania, Uganda, Zambia, Zimbabwe
Eligible products include medicines and medical devices for PPH prevention, diagnosis and treatment, specifically:
PPH medicines: Oxytocin, Misoprostol, HSC and TXA
PPH medical devices: Devices for objective measurement of blood loss such as calibrated drapes; Non-pneumatic anti-shock garment (NASG): NASGs are eligible if applicants can demonstrate the presence of functional referral and emergency transport systems to support introduction
Consumables such as IV fluids
All proposed products must be approved for introduction by the Ministry of Health as evidenced by the MOH endorsement letter, introduction and scale-up strategy, etc.
Both multi-product, bundled interventions and single-product interventions are eligible, provided they align with government rollout plans and country needs.
Projects focused on a single product or product-specific intervention should demonstrate how the proposed work fits within the Ministry of Health’s comprehensive approach for PPH management and what specific bottlenecks against the strategy their project would address.
Implementing timeframes will require no more than 12 months
Funding ceiling per application is a maximum of USD $250,000
Focus on public sector or private not-for-profit sector. The PPH COF doesn’t support private sector work at this time.
Funds may only be granted to non-governmental organizations, private not-for-profit entities, social marketing organizations (SMOs), or commercial entities.
Proposals focused on pilot or research projects designed to help the government make a decision whether to introduce or scale a product or intervention are not eligible.
For more details on the PPH COF and scoring rubrics that we use to assess applications, please see here: PPH COF Overview.
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Countries eligible for COF funding should already have made the decision to introduce the targeted product or intervention. Please note that pilot or research projects designed to help the government make the decision to introduce or scale are not eligible.
All activities must specifically support the government with planning or preparation for government-led introduction. Illustrative examples of eligible activities include:
PPH roadmap or scale-up strategy development or costed introduction plan
Updates to national guidelines and clinical protocols to adopt new products for PPH prevention, diagnosis and/or treatment
Development of national health care worker training curricula/plans
Updates to standard essential medicines/equipment lists to include new PPH products
Note: Non-profit/NGO entities are not eligible to support activities to support local regulatory authority approval. Social marketing organizations (SMOs) and commercial entities proposing to support local regulatory authority approval and country registration will be assessed on a case-by-case basis.
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Introduction preparation activities are underway (e.g., new products included in HMIS, LMIS, training curricula updated, national plan is in place, etc.).
Strong government endorsement, indicated by a PPH introduction and scale-up plan. Introduction strategies may be stand-alone PPH plans or embedded in other relevant strategies, such as broader maternal health and reproductive health plans. Note: national clinical guidelines or standards of care as evidence do not fulfill this requiement.
Local regulatory approval or written commitment to pursue an importation waiver by the project start date for the PPH products that your project is working on.
National guidelines and clinical protocols on PPH management and Essential Medicines List must include relevant PPH products that your project is working on.
Demonstrate there is sufficient stock of PPH medicines and devices in the country for relevant geographies or confirmed to be arriving in the country to support the needs of the proposed project.
Rationalized sequencing of activities that aligns supply availability and training.
Facility and healthcare worker cadre targets for introduction and training activities must be informed by national standards of care and aligned with recommended/appropriate service provision.
Proposed trainings should leverage cost-efficient, evidence-based models for delivery.
Routine activities (like EmONC training) may be eligible if applicants demonstrate they are critical to accelerating introduction and scale-up of eligible PPH products AND will be done in a catalytic way.
Catalytic procurement of models for training and/or activated facilities are eligible in instances of confirmed funding need, exhaustion of other options (e.g. rentals have been explored/exhausted), to catalyze procurement, and a plan for sustainability and replenishment is provided. Proportion of the budget for these equipment must be reasonable.
Illustrative examples of eligible activities include:
Conduct training of trainers on evidenced-based clinical interventions (E-MOTIVE) and new products such as HSC, TXA and drapes
Strengthening national coordination and partner coordination of PPH scale-up
Kick-starting new PPH supply planning, forecasting and quantification or updating to include new products (e.g., drapes, HSC)
Comparative cost analysis of single-use vs. reusable drapes to facilitate scale-up of a more cost-efficient drape option
Community-based distribution of misoprostol for PPH prevention
Submission Information
Prospective applicants are highly encouraged to determine their eligibility and readiness to apply to the PPH COF, using the PPH COF Readiness Tool Checklist.
Applications are reviewed on competitive application cycle. Interested applicants should submit the materials listed below to the COF Team at COF@clintonhealthaccess.org before the stipulated deadline published on this website.
In alignment with the refreshed and expanded scope, all Cycle 10 applicants must use the updated application templates, labeled “Version August 2025” to be considered for funding.
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Pre-Introduction Applications
1. Application Narrative in Word document format (EN)
2. Project Budget for the proposed activities (EN)
3. Letter of recommendation, or defined informal equivalent, from the National Ministry of Health
The intent behind this requirement is to ensure alignment of proposed projects to government plans and priorities. As you seek MOH endorsement, please engage in meaningful national coordination with key stakeholders and partners in-country to align on needs and project approaches prior to submission to avoid misalignment with government priorities and duplication of efforts.
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Active Introduction Applications
1. Application Narrative in Word document format (EN)
2. Project Budget for the proposed activities (EN)
3. Letter of recommendation, or defined informal equivalent, from the National Ministry of Health
The intent behind this requirement is to ensure alignment of proposed projects to government plans and priorities. As you seek MOH endorsement, please engage in meaningful national coordination with key stakeholders and partners in-country to align on needs and project approaches prior to submission to avoid misalignment with government priorities and duplication of efforts.
4. Country Government’s PPH Strategy and Plan, inclusive of for each target PPH product
5. Evidence of local regulatory approval for your project’s target PPH products or a written commitment to pursue a waiver if any of the products are new, for each target PPH product
6. Evidence of sufficient stock, for each target PPH product
7. Essential Medicine List or Clinical Guidelines that include each target PPH product
Projects may focus on one category or combine both types of activities within a single proposal. Proposals that include a mix of both pre-introduction and active introduction activities must fully meet the requirements for active introduction activities.
Resources
Interested in the projects and organizations supported by the COF? Click on the COF Project Directory for a list of past and current COF award recipients. This register includes project descriptions and points of contact. Please refer to this to ensure no duplication with existing or past awards, prompt local coordination with other partners, and build off of past work as relevant.