The Catalytic
Opportunity Fund

The Catalytic Opportunity Fund (COF) is a rapid response financing mechanism that supports introduction and scale-up of new and lesser-used reproductive health products in LMICs.

The COF is a flexible pool of funds to support time-bound projects and catalytic activities that advance introduction and scale-up. The COF has multiple product funding streams for Hormonal IUD (H-IUD), MA Combipacks, Postpartum Hemorrhage (PPH), and DMPA-SC self-injection.

Important Updates & Submission Deadlines

Upcoming Hormonal IUD COF Webinar: Join us for an informational webinar to provide an overview of the H-IUD COF scope, highlight recent updates, and walk prospective applicants through the application process on Wednesday, November 19 at 9:00 AM EDT. Register here.

Now Available: Updated H-IUD COF Application Materials: The H-IUD Application Narrative and Budget have been updated for Cycle 11 (January 2026). Visit the H-IUD COF page for full details and to access the new templates.

Upcoming Submission Deadlines: Applications for H-IUD, MA Combipacks, and PPH Product COFs (Cycle 11) are due Thursday, January 8, 2026, at 5:00 PM WAT.

Required Expression of Interest (EOI): All Cycle 11 prospective applicants must submit a short Expression of Interest (EOI) form before Tuesday, December 9, 2025 at 5:00 PM WAT. Applicants who do not submit an EOI on time will be ineligible to apply. EOI submissions for H-IUD, MA Combipacks, and PPH Products are now open. Access the form here.

COF Ethos and Principles

  • Catalytic, Time-Bound Opportunities

    Opportunities should have a clearly articulated impact to catalyze product introduction and scale-up, demonstration of funding needs, and alignment to the various definitions of “catalytic” for each of the funding streams.

    Opportunities should be time-bound projects (ranging from 9-12 months or less depending on which COF) with clear outcomes and results within the grant duration.

  • Country and Government Ownership

    The COF’s ethos is to provide funding that is aligned to government priorities and plans; shifting from traditional donor and partner top-down funding models toward greater country ownership.

    Opportunities are assessed on its merit for ensuring government-led introductions with the intention of enabling Ministries of Health to drive national priorities for introduction and ensure sustainable approaches to product scale-up.

  • Agile and Flexible Funding

    The COF is designed to rapidly deploy funding to allow for time-sensitive identification and action on catalytic opportunities; allowing grantees to repurpose funding to pivot to evolving government priorities and availability of funding through existing in-country programs identified during the grant.

  • Fair and Transparent Decision-Making

    Funding decisions follow a standardized process and are based on transparent criteria with input from relevant stakeholders in the SRH community

Read how the COF is delivering measurable outcomes here.

For more information on the H-IUD COF, MA Combipack COF, PPH Products, and DMPA-SC COF, please visit their dedicated pages.